INTRODUCING OVAGEN...

• Ovagen is a biotechnology company that has developed the process of producing germ free (GF) chicken eggs and GF birds in commercial quantities for use primarily in the pharmaceutical industry.

• Germ-free eggs are preferred as currently eggs produced from normal or SPF laying flocks can be infected with bacteria and viruses

• Germ-free eggs provide many advantages over current sources of eggs including:
A safe, biosecure, large scale, flexible and cost effective biomanufacturing platform for the production of vaccines and therapeutic proteins

• No contamination from eggs of batches of vaccines / therapeutic proteins / antisera
- Leads to cost saving and greater continuity of supply of finished product
- Removes risk of egg-derived contamination of pharmaceutical / vaccine manufacturing facilities

• GF eggs are produced to GMP fully compliant with USDA Memo 800.65 and European Pharmacopoeia requirements.

Applications of Germ Free (GF) Eggs/Cells/Tissues
Not only vaccines!

1. Conventional (prophylactic) vaccines
- Whole egg
- Primary cell cultures
- MVA-based (e.g. bioterrorism vaccines)
- Other pox virus based vaccines

2. Therapeutic vaccines
- Cancer vaccines (e.g. MVA-based Cervical (HPV) vaccine, Lung (NSC) vaccines)
- Infections agents (e.g. HIV)

3. Antibodies
- Polyclonal (e.g. snake antivenom)
- Monoclonal
   - Therapeutic (cancer, rheumatoid arthritis)
   - R&D (e.g. proteomics)
   - Diagnostics
   - Separation techniques (e.g. separation of stem cells from bone marrow)

4. Poultry Genetics (e.g. metacloning)

5. Pharmaceutical (e.g. hyaluronic acid, phospholipids)

NEW FACILITIES

December 2008 (2500msq)

• First generation germ-free flocks
• Isolators, Incubators
• Laboratories
• Pilot scale (25%) commercial production
• R&D
• Head Office

CONTACT

Ovagen Group Limited
Carrentrila,
Ballina,
Co. Mayo,
Ireland.

T. +353 (0)96 75579
E. info@ovagen.com